Concern
Compliment of your final response.
That is my time that is second I this question.
I have re-done a research that is thorough the physiology of male genitalia. Simply speaking, as it happens that information out there is inconsistent. In Wikipedia, two split entries of Foreskin’ and Mucous membrane’ yield contradictory outcomes: the previous states the glans penis (head associated with the penis) and glans clitoridis in addition to inside the prepuce (foreskin) and hood that is clitoral maybe not mucous membranes’, even though the latter says that the internal foreskin is a mucous membrane layer such as the inside the eyelid or the lips. ‘ in addition, relating to glans penis’ of wikipedia, The epithelium for the glans penis is mucocutaneous muscle.’
Because of the means we discovered that the foreskin consists of Langerhans cells that are recognized as receptor of HIV virus (these details arises from OU Handbook of GUM and HIV medicine).
We have talked about these problems having a psychiatrist (this is because i shouldn’t be doing penis-to-penis side-along rubbing and penis docking any more because `it’s rubbing of mucosal tissues that I feel I’m extremely worried over the whole HIV/STD thingy) who warned me. HIV/STD virus is likely to pass between. Why could you just just take such dangers?’
In your final response (answer that is last), you stated that the transmission threat of dick-docking is actually nonexistent and implied that penis-to-penis side-along rubbing does perhaps perhaps not pose any transmission danger considering that the only mucous membrane layer regarding the entire dick (including shaft, foreskin, glans penis) could be the liner of this urethra through the pee-hole up to the bladder. But i did not point out that i am uncircumcised. There is an abundance of internal foreskin whose extremely nature is very dubious of mucous membrane layer and which can be filled with Langerhans cells.
Therefore my questions are: (1) can you please reiterate your viewpoint regarding the transmission danger of dick-docking and penis-to-penis rubbing that is side-along citing the real reason for?? let’s say certainly one of us shot the strain? Would the strain shoot right at the urethra during docking. (2) should we put for a condom although we do dick-docking and penis-to-penis side-along rubbing? (3) can I execute a circumcision, as some studies from Kenya(!) recommend it reduces the possibility of transmission of HIV along with other STDs? Do it is believed by you?? (4) exactly why are Langerhans cells cited as vunerable to HIV infection? Exactly What part does it play ?? (5) exactly why is the definition of membrane that is `mucous so essential in HIV illness? what exactly is it anyway?? Would HIV or any other STDs have over the membrane layer and infect other people??
As bothersome that you wouldn’t find my queries offensive or devious in any way as I am, I sincerely do hope. Debate results in better understanding. To be able you painstakingly answer my questions? for me to have some sort of peace, could?
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Response
My estimation regarding HIV transmission/acquisition associated to frottage (penis-to-penis rubbing, “dick-docking”) remains unchanged. It isn’t regarded as a danger. Could a load is shot by you and hit the urethra? Yes, it really is theoretically feasible, but not more than likely, that the spunk would really come right into significant experience of the urethra’s mucous membrane layer.
If that will make you’re feeling safer much less anxious, yes. Individually, I do not feel it really is necessary.
The studies do indicate that male circumcision decreases the chance for acquiring HIV. But, I don’t feel it’s necessary if you follow safer sexual techniques.
Langerhan’s cells (dendritic cells) perform a crucial part in the initiation of HIV disease by virtue associated with ability of HIV to bind to certain mobile area receptors of the cells. This enables presentation that is efficient of to CD4 cells that then become contaminated. The foreskin contains Langerhan’s cells.
A mucous membrane layer is a slim layer (membrane layer) that lines all interior human anatomy passages that communicate straight with atmosphere outside of the human anatomy, like the breathing and alimentary tracts, and that has specialized cells or glands that secrete mucous. HIV can permeate mucous membranes, however it cannot permeate skin that is intact. The foreskin just isn’t a membrane that is mucous. Nevertheless, its a specific variety of epidermis and HIV may be taken on because of the Langerhan’s (dendritic) cells positioned in the foreskin.
We undoubtedly do not find your questions either devious or”offensive.” It could be somewhat confusing to attempt to explain complex information on physiology or even the purpose of specific cells in a forum similar to this forum. Therefore the physiology class has ended for today.